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61.
DE MAIO D 《Science (New York, N.Y.)》1959,129(3364):1678-1679
Diisopropylfluorophosphate inhibited all the sulfhydryl proteases studied in our tests. This inhibition was most pronounced at pH 6.0. By first blocking the sulfhydryl group with p-chloromercuribenzoate, inhibition could be prevented. Neither cysteine nor choline gave appreciable reactivation of diisopropylfluorophosphate-inhibited bromelain.  相似文献   
62.
Pharmacological evidence is presented supporting the theory that the increase in contractile strength of isolated cardiac muscle under suprathreshold stimulation is due to the release of an adrenergic mediator (norepinephrine). However, release of this material does not account for changes in contractile strength associated with changes in frequency of stimulation at threshold levels.  相似文献   
63.
The differentiation of benign vs. neoplastic lymph nodes impacts patient management. Specific sonographic features are typically considered when assessing lymph nodes in dogs. However, the usefulness of these criteria in distinguishing benign vs. malignant lymph nodes remains largely unknown, especially for deep lymph nodes. Our aim was to compare sonographic features in benign and neoplastic deep lymph nodes with the hope of identifying predictive criteria. Thirty‐one deep lymph nodes (16 mesenteric, 10 medial iliac, three hepatic, one sternal, and one cranial mediastinal) in 31 dogs were examined prospectively with B‐mode and Color flow Doppler. Lymph nodes were aspirated using ultrasound‐guidance and final diagnosis were established based on cytologic and/or histopathologic interpretation. Prevalence of each sonographic feature and combinations of two features was calculated for each group and compared using a χ2‐test or Student's t‐test for unequal variances. Ten lymph nodes were benign (hyperplastic and/or inflammatory) and 21 were neoplastic. All were hypoechoic, except for one neoplastic lymph node. Maximal short‐axis diameter (P=0.0006) and long‐axis diameter (P=0.01), and SA/LA ratio (P=0.008) were increased significantly for neoplastic (2.8, 5.5 cm, and 0.50, respectively) vs. benign (1.2, 3.8 cm, and 0.34, respectively) lymph nodes. The prevalence of other features was similar between groups. Doppler evaluation was possible in 77% of lymph nodes, but there was no significant difference between groups. When any two ultrasound features were combined, the only difference between benign and neoplastic lymph nodes was for the combination of contour regularity and appearance of the perinodal fat (P=0.03).  相似文献   
64.
65.
An attempt to predict engineering qualities which are needed in soil evaluation and to enhance nonagricultural use of soil survey data was made. Data from a variety of soils were subjected to simple correlation and multiple regression analyses to relate three pedologic characteristics: clay content, cation-exchange capacity (CEC), and organic matter content to two engineering qualitites: plasticity index, and optimum moisture. Simple correlation coefficients showed that clay content and CEC correlated significantly with the engineering determinations. The relationship between organic matter content and these engineering determinations was weaker. Multiple regression analyses showed that the three pedologic characteristics accounted for most of the variation in each of the engineering qualities, and that prediction was feasible.  相似文献   
66.
The alkaline extracts of an andic soil, a Bhir horizon of a spodic soil and leonardite which, after electrofocusing, displayed bands in the neutral region of the pH gradient, were fractionated by electrophoresis in phosphate buffer at pH 6.5. The non-migrated fraction gave an electrofocusing profile containing only bands focused at pH values above that of the electrophoretic separation. Electrophoresis in sodium acetate buffer pH 4.8 of humic substances extracted from peat permitted isolation of bands focusing above pH4.8. The distribution of metals after electrophoresis suggests that a great part of humic substances which originate bands above pH 6.5 consists of negatively charged Fe and Al complexes. Addition of EDTA to solutions of humic substances extracted from the samples resulted in the disappearance of bands in the neutral region of the pH gradient in the electrofocusing profile of the Bhir sample, while a consistent lessening of these bands was observed in the leonardite and andic soil samples.  相似文献   
67.
An explanation is put forward for the shape of adsorption envelopes found for phosphate adsorption by various metallic oxides. The equation xm= C1 (μH3PO4+μ∑anions) is proposed, where μH3pO4 is the chemical potential of undissociated H3PO4; μ∑anions is the chemical potential of all phosphate anions considered as one. component; C1 is a constant that includes influences of surface charge, chemical affinity of the metal for phosphate, specific surface area, etc., and xmis the calculated Langmuir maximum adsorption of P at each pH. The dependence of C1 on the metal present in the oxide is shown.  相似文献   
68.
Résumé— Cet article décrit un cas de nevus épidermique linéaire unilatéral chez un veau de six mois. Histologiquement, les lésions consistaient en une alternance de zones d'hiper et de parakératose avec une inflammation dermique distincte. Le diagnostic de nevus linéaire inflammatoire a été posé sur la base des lésions macro et microscopiques. [Deprez, P., De Coole, H., Sustronk, B., Muille, E., Ducatelle, R. A case of bovine linear keratosis (A propos d'un cas de kératose linéaire chez un bovin).
Resumen— En este artículo se describe un caso de nevos epidérmicos lineares unilaterales en un bo vino de seis meses de edad. Las lesiones histológicas consistian zonas donde se alternaba hiper i paraqueratosis, mientras que la dermis presentaba una marcada inflamación. Se diagnosticó un nevo epidérmico verrucoso linear e inflamatorio a partir de las lesiones clinicas e histopatológicas [A case of bovine linear keratosis (Un caso de queratosis linear bovina).
Abstract— This report describes a case of unilateral linear epidermal nevi in a 6-month-old bovine. Histologicalli, the lesions consisted of alternating areas of hiper- and parakeratosis with a distinct dermal inflammation. A diagnosis of inflammatori linear verrucous epidermal nevus was made based on the clinical and histopathological lesions.  相似文献   
69.
Two strains of rabbits (strains 1077 and 2066) have been selected since 1974 for increased litter size. Each strain is split into a fixed number of reproduction groups. The mating scheme is similar to random non-sib herd mating. The number of animals per generation is higher in strain 1077 (28 mated bucks and 104 mated does) than in strain 2066 (17 and 59, respectively). The increase of the inbreeding coefficient is higher in strain 2066 than in strain 1077 (27 and 21%, respectively, at generation 20). The mean standard deviation of the individual inbreeding coefficients per generation is low (less than 4%) in both strains. Short-term inbreeding is stable over generations. The observed inbreeding effective size Ne f and the observed familial structure effective size Ne h converge to the same value. The number of founder genomes still present in the genetic pool of the generation decreases regularly: from 5.6 to 2.4 between G6 and G20 for strain 1077. It is a bit lower over time for strain 2066 (from 5.7 to 1.9 between G6 and G20). The effective number of founders is nearly twice as small as the total number: 30 for strain 1077 and 15 for strain 2066. The effective number of major ancestors decreases slightly in strain 1077 (13.6 in G6 and 12.9 in G20) and regularly in strain 2066 (13.8 in G6 and 9.4 in G20).  相似文献   
70.
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